The property has two retail areas, Wynn Esplanade and Wynn Plaza, the latter replacing the dealership in 2018.

Upon opening, the resort also included the state's only Ferrari and Maserati dealership, which later closed in 2015. The Desert Inn's golf course was kept and redesigned to become the Wynn's course. A 3-acre (1.2 ha) lake is surrounded by the mountain and several restaurants, and is the site of a show called Lake of Dreams, which features singing animatronics. Instead, an artificial mountain obscures most of the attractions, meant to evoke curiosity and lure people into the resort. In a break from Wynn's previous resorts, it also lacks a free attraction for pedestrians.

Unlike most Strip resorts, the Wynn does not feature a theme. Wynn declared his $5.2 billion complex finished in May 2010, following additions made at Encore. Located directly north of the resort, Encore added a second hotel tower and additional gaming space, as well as several restaurants and clubs. A sister property, Encore Las Vegas, was opened by Wynn Resorts in December 2008. At the time, its 45-story hotel tower was the tallest building in Nevada. At a cost of $2.7 billion, Wynn Las Vegas was the most expensive resort ever built, beating Wynn's $1.6 billion Bellagio, which opened on the Strip in 1998. The design phase lasted two and a half years, and construction began on October 31, 2002, with Marnell Corrao Associates as general contractor. Casino developer Steve Wynn purchased and closed the Desert Inn during 2000, with plans to build a new resort on the site. It is owned and operated by Wynn Resorts, and was built on the former site of the Desert Inn resort, which opened in 1950. Wynn Las Vegas, often simply referred to as Wynn, is a luxury resort and casino located on the Las Vegas Strip in Paradise, Nevada, United States.

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